The Sheraton Centre Toronto Hotel is close to all the major attractions of the city center, including PATH, a 16-mile underground shopping complex. City Hall, the Toronto Stock Exchange, and several theaters are also a short walk away. The CN Tower and the Air Canada Center are easily accessible by car or public transportation. The Sheraton Centre Toronto Hotel is connected to the subway and railway via PATH, the underground network of shops.

The 1377 guestrooms at the Sheraton Centre Toronto Hotel each feature special pillow-top beds with down pillows and comforters. High-speed Internet is accessible in every room as well. Guestrooms also feature large desks, TVs, and video game consoles. Guest with dogs can enjoy dog beds, bowls, mats, and ID tags in their rooms as well.

The Sheraton Centre Toronto Hotel is set on several acres of manicured grounds, which include a tranquil waterfall garden. A full-service spa and three restaurants are located inside the building. Other amenities include conference rooms, 24-hour front desk services, dry cleaning and laundry, an outdoor pool, and a fitness center.